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Research Article Open Access

Synthesis and Characterization of Inclusion Complex of Carbamide with Extremely Branched, Globular, Mono-Disperse, Nanometric Starburst PAMAM Dendrimer


Prashik M. Walke, Jyotsna S. Meshram


1Department of Chemistry, Sant Gadge Maharaj Mahavidyalaya, Hingna, RTM Nagpur University, Nagpur 441110, India

2Department of Chemistry, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur 440033, India

Adv. Mater. Proc., 2020, 5 (3), 20030405

DOI: 10.5185/amp.2020.030405

Publication Date (Web):04/07/2020

Copyright © IAAM-VBRI Press


All Dendrimers are the emerging polymeric architectures known for their defined structure, low polydispersity, nanometric size and high functionality. These nanostructure macromolecules have shown their potential abilities in entrapping and conjugating the high molecular weight hydrophobic or hydrophilic entities by host-guest interaction and covalent bonding respectively. Dendrimer is the irresistible candidature for the formation of inclusion complexes capable of accomplishing the various applications. This is due to the presence of various terminal groups with varied functionalities. PAMAM Dendrimer has been growing interest because of their unique characteristics like globular, nanoscale, macromolecule with different functionalities at periphery. PAMAM is comparatively novel group of these distinctive materials that is grown from the core side and each half or complete generation needs some repeating reactions. Also it has potential applicability in a wide range of areas makes it the promising candidate for lots of applications.Herein, we have synthesized Polyamidoamine (PAMAM) dendrimer of various generations and characterized by Fourier transform infrared (FTIR) spectroscopy and Mass spectrometry. The -0.5G PAMAM has differential functionality and special characteristics which allows the formation of inclusion complexes with various molecules. At this place, the inclusion complexes formed with carbamide molecules, which implant more functionality through host-guest interaction compared to the host molecules 


Dendrimer, PAMAM, host-guest, inclusion complex.