1Shanghai Key Laboratory of Functional Materials Chemistry and Research Centre of Analysis and Test, East China, University of Science and Technology, Shanghai 200237, P. R. China
2State Key Laboratory of Bioreactor Engineering. East China University of Science and Technology, Shanghai 200237, P. R. China
Adv. Mater. Lett., 2011, 2 (3), pp 172-175
Publication Date (Web): Apr 08, 2012
Copyright © IAAM-VBRI Press
Novel spin-labeled magnetic nanoparticles (MNPs) were prepared through the reaction between carboxylic acids modified Fe3O4 particles and 4-amino-2,2,6,6-tetramethylpiperidin-1-oxyl (4-NH2-TEMPO). And X-ray diffractometer (XRD), FT-IR spectra, thermogravimetric analysis (TGA), transmission electronic microscopy (TEM) and room temperature electron paramagnetic resonance (EPR) were employed to characterize the prepared materials. The results of EPR measurements indicated that the spin-labeled MNPs exhibited both the paramagnetism of nitroxide free radicals and superparamagnetism of ferrimagnetic nanoparticles could act as a bio-probe or potential drug delivery vehicles tracking by EPR technique.
Multifunctional magnetic nanoparticles (MNPs), spin labeled, electron paramagnetic resonance (EPR), bio-probes, drug delivery