Interaction of bovine serum albumin with synthetic spiropyrimidines

Notice (8): Trying to get property of non-object [APP/Controller/ArticlesController.php, line 300]

                $Issues_articles_image=$this->loadModel('Issues')->find('all')->where(['status'=>'1','admin_delete'=>'0','id'=>$article->volume])->order(['id' => 'DESC'])->first();
        
                $coverimage_artciles='/aml/uploads/coverimage/'.$Issues_articles_image->coverimage_file;

$id = '775'
$issue = object(Cake\ORM\Table) {

	'registryAlias' => 'Issues',
	'table' => 'issues',
	'alias' => 'Issues',
	'entityClass' => '\Cake\ORM\Entity',
	'associations' => [],
	'behaviors' => [],
	'defaultConnection' => 'default',
	'connectionName' => 'default'

}
$article_current = object(Cake\ORM\Table) {

	'registryAlias' => 'Articles',
	'table' => 'articles',
	'alias' => 'Articles',
	'entityClass' => '\Cake\ORM\Entity',
	'associations' => [],
	'behaviors' => [],
	'defaultConnection' => 'default',
	'connectionName' => 'default'

}
$article = object(Cake\ORM\Entity) {

	'id' => (int) 775,
	'user_id' => (int) 0,
	'volume' => (int) 72,
	'volumeno' => (int) 7,
	'issuseno' => (int) 1,
	'issusemonth' => 'January',
	'issuseyear' => '2016',
	'title' => '<p>Interaction Of Bovine Serum Albumin With Synthetic Spiropyrimidines</p>
',
	'meta_title' => 'Interaction of bovine serum albumin with synthetic spiropyrimidines',
	'meta_desc' => 'Interaction of bovine serum albumin with synthetic spiropyrimidines',
	'meta_keyword' => 'Spiropyrimidines, BSA, fluorescence, energy transfer, CD.',
	'alias_name' => 'interactionofbovineserumalbuminwithsyntheticspiropyrimidines',
	'authorname' => '<p>Swarup Roy<sup>1</sup>, Sudipta Ponra<sup>2</sup>, Tapas Ghosh<sup>2</sup>, K.C. Majumdar<sup>2*</sup> and Tapan Kumar Das<sup>1*</sup></p>
',
	'authorfrontname' => 'Swarup Roy, Sudipta Ponra, Tapas Ghosh, K.C. Majumdar and Tapan Kumar Das',
	'authoraffiliation' => '<p><em><sup>1</sup></em><em>Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India</em></p>

<p><em><sup>2</sup></em><em>Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India</em></p>
',
	'authoremail' => '<p>E-mail: tapankumardas175@gmail.com,kcmklyuniv@gmail.com</p>
',
	'authorbiography' => '',
	'page' => '65-70',
	'pagesequence' => '12',
	'doi' => '10.5185/amlett.2016.6081',
	'articletype' => '1',
	'keyword' => '<p>Spiropyrimidines, BSA, fluorescence, energy transfer, CD.</p>
',
	'abstractpdf' => null,
	'abstractdec' => '<p style="text-align:justify"><span style="font-size:10pt">Study of interaction between synthetic spiropyrimidines (SP) with bovine serum albumin (BSA) was investigated by spectroscopy. The fluorescence of BSA was quenched by SP by means of static quenching mechanism. Using Stern&ndash;Volmer analysis of the fluorescence quenching data number of binding sites (n) and binding constants (K) at different temperatures were computed. The thermodynamic parameters enthalpy change (&Delta;H) and entropy change (&Delta;S) were calculated using Van&rsquo;t Hoff equation (&Delta;H = -95.16 kJ/mol and &Delta;S = -251.49 J/mol/ K) and the results clearly indicated binding process is enthalpy-driven but entropically disfavored. The weak force van der Waals interaction and hydrogen bonding is responsible for BSA-SP complexation. Synchronous fluorescence, UV-Vis and circular dichroism (CD) spectra proposed possibility of alteration in conformation of BSA in the presence of SP. Using Forster&rsquo;s non-radiation energy transfer (FRET) theory distance between the donor and the acceptor were found to be &lt;7 nm. </span>&nbsp;</p>
',
	'fullabstractpdf' => '56797f27e60fa1450802983_fullabstratct.pdf',
	'fullabstractdesc' => '',
	'supporting_information' => null,
	'tocimage' => '',
	'received' => '',
	'accepted_for_publication' => '',
	'checked_for_plagiarism' => 'Yes',
	'review_by' => '',
	'peer_reviewers_approved_by' => '',
	'peer_reviewer_comments' => '',
	'editor_who_approved_publication' => '',
	'created' => object(Cake\I18n\FrozenTime) {},
	'modified' => '2015-12-22 09:49:43',
	'sequence' => (int) 12,
	'status' => (int) 1,
	'published' => (int) 1,
	'mostcitedissue' => (int) 0,
	'view_counts' => (int) 0,
	'count_download' => (int) 0,
	'admin_delete' => (int) 0,
	'citation_author' => null,
	'citation_author_institution' => null,
	'last_page' => (int) 0,
	'article_html_data' => null,
	'refernece' => null,
	'[new]' => false,
	'[accessible]' => [
		'*' => true
	],
	'[dirty]' => [],
	'[original]' => [],
	'[virtual]' => [],
	'[errors]' => [],
	'[invalid]' => [],
	'[repository]' => 'Articles'

}
$issue_article = 'Volume 7, Issue 1, Article ID  65-70, January 2016'
$Issues_articles_image = null
$coverimage_artciles = ''
$coverimage_desc = ''
$issue_data = object(Cake\ORM\Entity) {

	'id' => (int) 532,
	'type' => '21',
	'volumenumber' => '12',
	'issusenumber' => '8',
	'issusemonth' => 'August',
	'issuseyear' => '2021',
	'pageno' => '21081650-21081657',
	'sequence' => (int) 1,
	'coverimage_file' => '128x170pxCover_1625741389.jpg',
	'coverimagepdf_file' => null,
	'coverimage_desc' => '<p style="text-align:justify">The present scenario of the world climate shows that climate change and environmental degradation are a major cause of worry for the whole world and an immediate treatment into the situation is the utmost need of the hour. International Association of Advanced Materials also synchronizes its agenda &ldquo;Advancement of Materials to Sustainable and Green World&rdquo; with the action plans of the European Green Deal which is aimed at making Europe climate neutral by 2050 for which they have taken a set of policy initiatives. The cover photo of this August 2021 issue of Advanced Materials Letters is inspired by the <strong><a href="https://www.vbripress.com/aml/pdf/1646" target="_blank">editorial article</a></strong> by Dr. Ashutosh Tiwari.</p>
',
	'download_count' => (int) 0,
	'admin_delete' => (int) 0,
	'status' => (int) 1,
	'created' => null,
	'modified' => object(Cake\I18n\FrozenTime) {},
	'[new]' => false,
	'[accessible]' => [
		'*' => true
	],
	'[dirty]' => [],
	'[original]' => [],
	'[virtual]' => [],
	'[errors]' => [],
	'[invalid]' => [],
	'[repository]' => 'Issues'

}

App\Controller\ArticlesController::details() - APP/Controller/ArticlesController.php, line 300
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 429
Cake\Routing\Dispatcher::_invoke() - CORE/src/Routing/Dispatcher.php, line 114
Cake\Routing\Dispatcher::dispatch() - CORE/src/Routing/Dispatcher.php, line 87
[main] - ROOT/webroot/index.php, line 51

Notice (8): Trying to get property of non-object [APP/Controller/ArticlesController.php, line 302]

Code Context

                $coverimage_artciles='/aml/uploads/coverimage/'.$Issues_articles_image->coverimage_file;
        
                $coverimage_desc=$Issues_articles_image->coverimage_desc;

$id = '775'
$issue = object(Cake\ORM\Table) {

	'registryAlias' => 'Issues',
	'table' => 'issues',
	'alias' => 'Issues',
	'entityClass' => '\Cake\ORM\Entity',
	'associations' => [],
	'behaviors' => [],
	'defaultConnection' => 'default',
	'connectionName' => 'default'

}
$article_current = object(Cake\ORM\Table) {

	'registryAlias' => 'Articles',
	'table' => 'articles',
	'alias' => 'Articles',
	'entityClass' => '\Cake\ORM\Entity',
	'associations' => [],
	'behaviors' => [],
	'defaultConnection' => 'default',
	'connectionName' => 'default'

}
$article = object(Cake\ORM\Entity) {

	'id' => (int) 775,
	'user_id' => (int) 0,
	'volume' => (int) 72,
	'volumeno' => (int) 7,
	'issuseno' => (int) 1,
	'issusemonth' => 'January',
	'issuseyear' => '2016',
	'title' => '<p>Interaction Of Bovine Serum Albumin With Synthetic Spiropyrimidines</p>
',
	'meta_title' => 'Interaction of bovine serum albumin with synthetic spiropyrimidines',
	'meta_desc' => 'Interaction of bovine serum albumin with synthetic spiropyrimidines',
	'meta_keyword' => 'Spiropyrimidines, BSA, fluorescence, energy transfer, CD.',
	'alias_name' => 'interactionofbovineserumalbuminwithsyntheticspiropyrimidines',
	'authorname' => '<p>Swarup Roy<sup>1</sup>, Sudipta Ponra<sup>2</sup>, Tapas Ghosh<sup>2</sup>, K.C. Majumdar<sup>2*</sup> and Tapan Kumar Das<sup>1*</sup></p>
',
	'authorfrontname' => 'Swarup Roy, Sudipta Ponra, Tapas Ghosh, K.C. Majumdar and Tapan Kumar Das',
	'authoraffiliation' => '<p><em><sup>1</sup></em><em>Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India</em></p>

<p><em><sup>2</sup></em><em>Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India</em></p>
',
	'authoremail' => '<p>E-mail: tapankumardas175@gmail.com,kcmklyuniv@gmail.com</p>
',
	'authorbiography' => '',
	'page' => '65-70',
	'pagesequence' => '12',
	'doi' => '10.5185/amlett.2016.6081',
	'articletype' => '1',
	'keyword' => '<p>Spiropyrimidines, BSA, fluorescence, energy transfer, CD.</p>
',
	'abstractpdf' => null,
	'abstractdec' => '<p style="text-align:justify"><span style="font-size:10pt">Study of interaction between synthetic spiropyrimidines (SP) with bovine serum albumin (BSA) was investigated by spectroscopy. The fluorescence of BSA was quenched by SP by means of static quenching mechanism. Using Stern&ndash;Volmer analysis of the fluorescence quenching data number of binding sites (n) and binding constants (K) at different temperatures were computed. The thermodynamic parameters enthalpy change (&Delta;H) and entropy change (&Delta;S) were calculated using Van&rsquo;t Hoff equation (&Delta;H = -95.16 kJ/mol and &Delta;S = -251.49 J/mol/ K) and the results clearly indicated binding process is enthalpy-driven but entropically disfavored. The weak force van der Waals interaction and hydrogen bonding is responsible for BSA-SP complexation. Synchronous fluorescence, UV-Vis and circular dichroism (CD) spectra proposed possibility of alteration in conformation of BSA in the presence of SP. Using Forster&rsquo;s non-radiation energy transfer (FRET) theory distance between the donor and the acceptor were found to be &lt;7 nm. </span>&nbsp;</p>
',
	'fullabstractpdf' => '56797f27e60fa1450802983_fullabstratct.pdf',
	'fullabstractdesc' => '',
	'supporting_information' => null,
	'tocimage' => '',
	'received' => '',
	'accepted_for_publication' => '',
	'checked_for_plagiarism' => 'Yes',
	'review_by' => '',
	'peer_reviewers_approved_by' => '',
	'peer_reviewer_comments' => '',
	'editor_who_approved_publication' => '',
	'created' => object(Cake\I18n\FrozenTime) {},
	'modified' => '2015-12-22 09:49:43',
	'sequence' => (int) 12,
	'status' => (int) 1,
	'published' => (int) 1,
	'mostcitedissue' => (int) 0,
	'view_counts' => (int) 0,
	'count_download' => (int) 0,
	'admin_delete' => (int) 0,
	'citation_author' => null,
	'citation_author_institution' => null,
	'last_page' => (int) 0,
	'article_html_data' => null,
	'refernece' => null,
	'[new]' => false,
	'[accessible]' => [
		'*' => true
	],
	'[dirty]' => [],
	'[original]' => [],
	'[virtual]' => [],
	'[errors]' => [],
	'[invalid]' => [],
	'[repository]' => 'Articles'

}
$issue_article = 'Volume 7, Issue 1, Article ID  65-70, January 2016'
$Issues_articles_image = null
$coverimage_artciles = '/aml/uploads/coverimage/'
$coverimage_desc = ''
$issue_data = object(Cake\ORM\Entity) {

	'id' => (int) 532,
	'type' => '21',
	'volumenumber' => '12',
	'issusenumber' => '8',
	'issusemonth' => 'August',
	'issuseyear' => '2021',
	'pageno' => '21081650-21081657',
	'sequence' => (int) 1,
	'coverimage_file' => '128x170pxCover_1625741389.jpg',
	'coverimagepdf_file' => null,
	'coverimage_desc' => '<p style="text-align:justify">The present scenario of the world climate shows that climate change and environmental degradation are a major cause of worry for the whole world and an immediate treatment into the situation is the utmost need of the hour. International Association of Advanced Materials also synchronizes its agenda &ldquo;Advancement of Materials to Sustainable and Green World&rdquo; with the action plans of the European Green Deal which is aimed at making Europe climate neutral by 2050 for which they have taken a set of policy initiatives. The cover photo of this August 2021 issue of Advanced Materials Letters is inspired by the <strong><a href="https://www.vbripress.com/aml/pdf/1646" target="_blank">editorial article</a></strong> by Dr. Ashutosh Tiwari.</p>
',
	'download_count' => (int) 0,
	'admin_delete' => (int) 0,
	'status' => (int) 1,
	'created' => null,
	'modified' => object(Cake\I18n\FrozenTime) {},
	'[new]' => false,
	'[accessible]' => [
		'*' => true
	],
	'[dirty]' => [],
	'[original]' => [],
	'[virtual]' => [],
	'[errors]' => [],
	'[invalid]' => [],
	'[repository]' => 'Issues'

}

App\Controller\ArticlesController::details() - APP/Controller/ArticlesController.php, line 302
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 429
Cake\Routing\Dispatcher::_invoke() - CORE/src/Routing/Dispatcher.php, line 114
Cake\Routing\Dispatcher::dispatch() - CORE/src/Routing/Dispatcher.php, line 87
[main] - ROOT/webroot/index.php, line 51

Interaction Of Bovine Serum Albumin With Synthetic Spiropyrimidines

Swarup Roy¹, Sudipta Ponra², Tapas Ghosh², K.C. Majumdar^2* and Tapan Kumar Das^1*

¹Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India

²Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India

Adv. Mater. Lett., 2016, 7 (1), pp 65-70

DOI: 10.5185/amlett.2016.6081

Publication Date (Web): Dec 22, 2015

E-mail: tapankumardas175@gmail.com,kcmklyuniv@gmail.com

Full Article

Abstract

Study of interaction between synthetic spiropyrimidines (SP) with bovine serum albumin (BSA) was investigated by spectroscopy. The fluorescence of BSA was quenched by SP by means of static quenching mechanism. Using Stern–Volmer analysis of the fluorescence quenching data number of binding sites (n) and binding constants (K) at different temperatures were computed. The thermodynamic parameters enthalpy change (ΔH) and entropy change (ΔS) were calculated using Van’t Hoff equation (ΔH = -95.16 kJ/mol and ΔS = -251.49 J/mol/ K) and the results clearly indicated binding process is enthalpy-driven but entropically disfavored. The weak force van der Waals interaction and hydrogen bonding is responsible for BSA-SP complexation. Synchronous fluorescence, UV-Vis and circular dichroism (CD) spectra proposed possibility of alteration in conformation of BSA in the presence of SP. Using Forster’s non-radiation energy transfer (FRET) theory distance between the donor and the acceptor were found to be <7 nm.

Keywords

Spiropyrimidines, BSA, fluorescence, energy transfer, CD.

Full Article

<< Previous article in issue

Next article in issue >>

⊕ Current Issue

Advancing Materials towards Climate Neutrality by 2050

⊕View details

Full Article

Efficiency of Nanomaterials for Electrochemical Diagnostics based Point-of-Care Detection of Non-Invasive Oral Cancer Biomarkers

⊕View details

Full Article

Hybrid Membrane based on Polymer-doped Phosposilicate and their Characterization

⊕View details

Full Article

A DFT Study of Interaction of (CdSe)₃ Quantum Dots with Nucleobases

⊕View details

Full Article

Low Resistance and High Electromigration Lifetime of Cu-To-Cu Joints Using (111)-Oriented Nanotwinned Copper

⊕View details

Full Article

Electrochemical Hydrogen Evolution Reaction Triggered by Co_2xMo_1-xS₂ (x = 0. 0.05 and 0.1) in Acidic Medium

⊕View details

Full Article

Effect of La Dopant in Modified Bismuth Ferrite Ceramics

⊕View details

Full Article

Biogenic Capped Silver Nanoparticles in Lablal Purpureus Pod Extract Exhibit Selective Antibacterial and Synergistic Anticancer Activity

⊕View details

Full Article

⊕ Previous issues

Transforming Paradigm of Artificial Intelligence for Scalable Clinical Healthcare

⊕View details

Full Article

A Review on Harnessing Nanomaterials as Promising Materials Interface

⊕View details

Full Article

A New Epidemic Spreading Model to Predict the Spread and Accumulation of Corona Virus (COVID-19) Positive Cases as a Function of Time

⊕View details

Full Article

Green Synthesis of ZnO and Ag-ZnO Nanoparticles using Macrotyloma Uniflorum: Evaluation of Antibacterial Activity

⊕View details

Full Article

Feature Behavior of Resistivity in Bi Foils Obtained by a Melt Spinning Method

⊕View details

Full Article

Thermomagnetic Properties of Metal and Metal-oxide Nanoparticles

⊕View details

Full Article

Effect on Structural, Electrical and Temperature Sensing behavior of Neodymium Doped Bismuth Ferrite

⊕View details

Full Article

Novel Green Chemistry Synthesis of Nano-Hydroxyapatite using Soya Milk as a Natural Stabiliser

⊕View details

Full Article

Upcoming Congress

Knowledge Experience at Sea ^TM

⊕Recommended Articles

Reply to commentary on "Spectral characterizatiob of the building...

⊕View details

Purchase PDF

Reply to commentary on "Spectral characterizatiob of the building...

⊕View details

Purchase PDF

Reply to commentary on "Spectral characterizatiob of the building...

⊕View details

Purchase PDF

advanced search

Interaction Of Bovine Serum Albumin With Synthetic Spiropyrimidines

1Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India 2Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India

Abstract

Keywords

Upcoming Congress

Knowledge Experience at Sea TM

⊕Recommended Articles

We Social

¹Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India

²Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India

Knowledge Experience at Sea ^TM