1Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
2School of Sciences, NetajiSubhas Open University, Kolkata 700064, India
3Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India
Adv. Mater. Lett., 2015, 6 (11), pp 1018-1024
DOI: 10.5185/amlett.2015.5933
Publication Date (Web): Oct 26, 2015
Copyright © IAAM-VBRI Press
E-mail: tapankumardas175@gmail.com, kcmklyuniv@gmail.com
The interaction between pyrimidine-annulated spiro-dihydrofuran (PSDF) with bovine serum albumin (BSA) was investigated following spectroscopic studies. The results indicate that dynamic quenching contributes to the fluorescence quenching of BSA by PSDF. The binding constant (K) and the number of binding sites (n) were calculated from the recorded spectra. Based on the Förster’s non-radiative energy transfer theory, the average binding distance between BSA and PSDF was estimated. The synchronous fluorescence spectra and circular dichroism indicate that the conformation of BSA has been subjected to alteration in presence of PSDF. The thermodynamic parameters namely ΔH, ΔG, ΔS were calculated at different temperatures (20 oC, 30 oC, and 40 oC) and the results indicated van der Waals force and hydrogen bonding were predominantly present. The compound PSDF also found to exhibit antifungal activity against Aspergillus sp. In addition, the results obtained from molecular modeling calculation vividly elucidate the binding mode and the binding sites and results were not well in agreement with the experimental observations.
Trade-off between Safety of Construction Workers and Economy in Backdrop of Covid-19
Recent Applications of Magnesium Oxide (MgO) Nanoparticles in various domains
Influence of Coating Thickness on the Formability of Annealed Aluminum 2024
Nonwovens with and without Super-absorbents Surface Help Firefighters as Additional Active-Cooling to Prevent Heat-Related Deaths
Enhanced Electrochemical Reduction of CO2 by Zeolitic Imidazolate Frameworks-8 Supported Silver Nanoparticles
Effect of Surfactant type on the Characteristics and Bioactivity of Mesoporous Bioactive Glasses
Structure Factor of Charged Microemulsion Nanodroplets Decorated with Telechelic Polymers: Experimental and Numerical Study
The Catalytic Efficiency of Au3+ metal ions and Au NPs on the Oxidation of Carbonyl Compounds by in situ Generated Na2FeO4 under Microwave Irradiation for Industrial Point of View
Synthesis, Functionalized and Characterization of Magnetic Fe3O4 Nanoparticles Protected with MCM-41 Mesoporous
Adaptations and Lessons from COVID-19: A Perspective on How some Industries will be Impacted
Background and Strategies for Identification and Design of Materials for Thermochemical Energy Storage and Conversion
Phosphorus Gasification during the Reduction of basic Oxygen Furnace Slags in a Novel Reactor Concept
Concrete Electrical Resistivity at Varied Water, Chloride Contents and Porosity – Experiment, Modelling & Application
Water Purifying Bio-concrete
Local Fluctuations of Transformation to “Amorphous Diamond” from C60 Fullerenes and Neutron-irradiated Graphite under Shock-compression
Coulomb Drag of Electron-Electron Interactions in GaAs Bilayer with a Non Homogeneous Dielectric Background
Effect of Nd-concentration in Nd(2-x)FexO3 System on the Crystal Structure and Microwave Absorption Characteristics
Experimental Study on Strength Characteristics of Chopped Glass Fiber (CGF) Cement-Mortar Composites
Copyright ©2010-2020 VBRI Press
Full Article