1Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
2Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India
Adv. Mater. Lett., 2015, 6 (10), pp 913-919
DOI: 10.5185/amlett.2015.5931
Publication Date (Web): Sep 18, 2015
Copyright © IAAM-VBRI Press
E-mail: tapankumardas175@gmail.com, kcmklyuniv@gmail.com
The study of interaction between spirooxindole-annulated thiopyran derivatives (STP) and bovine serum albumin (BSA) was investigated using multi-spectroscopic and docking method. The intrinsic fluorescence of BSA could effectively quenched by STP through dynamic quenching. The thermodynamic parameters suggested that hydrogen bonds and van der Waals forces played a key role in stabilizing the BSA–STP complexes. According to Forster non radiation energy transfer theory (FRET) the average binding distance (r) between STP and BSA were found to be < 7 nm. Furthermore, UV-visible and circular dichroism results indicated that in presence of STP secondary structure of BSA changed. Theoretical docking study of the interaction of BSA and STP also supported the experimental results.
Advancing Materials towards Climate Neutrality by 2050
Efficiency of Nanomaterials for Electrochemical Diagnostics based Point-of-Care Detection of Non-Invasive Oral Cancer Biomarkers
Hybrid Membrane based on Polymer-doped Phosposilicate and their Characterization
A DFT Study of Interaction of (CdSe)3 Quantum Dots with Nucleobases
Low Resistance and High Electromigration Lifetime of Cu-To-Cu Joints Using (111)-Oriented Nanotwinned Copper
Electrochemical Hydrogen Evolution Reaction Triggered by Co2xMo1-xS2 (x = 0. 0.05 and 0.1) in Acidic Medium
Effect of La Dopant in Modified Bismuth Ferrite Ceramics
Biogenic Capped Silver Nanoparticles in Lablal Purpureus Pod Extract Exhibit Selective Antibacterial and Synergistic Anticancer Activity
Transforming Paradigm of Artificial Intelligence for Scalable Clinical Healthcare
A Review on Harnessing Nanomaterials as Promising Materials Interface
A New Epidemic Spreading Model to Predict the Spread and Accumulation of Corona Virus (COVID-19) Positive Cases as a Function of Time
Green Synthesis of ZnO and Ag-ZnO Nanoparticles using Macrotyloma Uniflorum: Evaluation of Antibacterial Activity
Feature Behavior of Resistivity in Bi Foils Obtained by a Melt Spinning Method
Thermomagnetic Properties of Metal and Metal-oxide Nanoparticles
Effect on Structural, Electrical and Temperature Sensing behavior of Neodymium Doped Bismuth Ferrite
Novel Green Chemistry Synthesis of Nano-Hydroxyapatite using Soya Milk as a Natural Stabiliser
Copyright ©2010-2021 VBRI Press
Full Article