How Ethanol Treatment Affects The Physico-chemical And Biological Characteristics Of Silk Fibroin Nanofibrous Scaffolds
Mazaher Gholipourmalekabadi1*, Masoud Mozafari2*, Mojgan Bandehpour1, 3, Marzieh Sameni1, Hossein Ghanbarian1
1Biotechnology Department, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2Bioengineering Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), P.O. Box 14155-4777, Tehran, Iran
3Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Adv. Mater. Lett., 2015, 6 (5), pp 391-394
DOI: 10.5185/amlett.2015.5739
Publication Date (Web): May 05, 2015
Copyright © 2019 VBRI Press
E-mail: mazaher.gholipour@gmail.com
In this study, the effects of ethanol treatment on the mechanical and biological characteristics of the nanofibrous silk fibroin (NSF) scaffolds were evaluated. The results obtained from the mechanical tests confirmed that ethanol treatment significantly enhanced the physical properties of the scaffolds through the formation of a ß-sheet structure. It was shown that the ethanol treatment increased the mechanical property and cell viability, while decreased the porosity of the randomly arranged uniform nanofibers. The ultimate tensile strength for the NSF and ethanol-treated NSF (ET-NSF) scaffolds were 0.76 and 1.33 MPa, respectively. In addition, the ethanol treatment positively affected the proliferation rate of rat bone-marrow stromal cells (rBMSCs) without any detectable cytotoxicity. All the results obtained from this study strongly indicated the efficacy of ethanol treatment in enhancement of mechanical and biological characteristics of silk fibroin nanofibrous scaffolds.
Silk fibroin, tissue engineering, electrospinning, mechanical properties, ethanol treatment.
Researcher of the Year 2019: Professor Enge Wang – A Legendary Researcher of Atomistic World
Graphene in Russia: The Main Centers, Research Areas, Results
Principles and practices of Si light emitting diodes using dressed photons
Dual Effect of Light Irradiation for Surface Relief Gratings Formation in Se-rich Ge-Se Thin Films
Synthesis, Structural Characterization, Dielectric and Piezoelectric Properties of Multiferroic Double-perovskite Bi2FeMnO6 Ceramics
Anisotropic and Nonlinear Mechanical Properties in Two-dimensional Nanomaterials
Anisotropy of Mechanical Properties of an AZ31 Alloy Prepared by SPD Method
Validation of Advanced Constitutive Models for Accurate FE Modeling of TPU
Alignment of Rods and Flakes using Electric Field
Shape Memory Polymer Composites for Long-Term Exposure to Space Environment
In-soil Biodegradation Behavior of Chitosan-Coated Phosphorylated Starch Films
Adaptive FRP Structures for Exterior Applications
Characterization of Plasma Activated Water for Medical Applications
Current Global Scenario of Electric Vehicles
Review on Detection of Phenol in Water
Investigating the Machinability of Metallic Matrix Composites Reinforced by Carbon Nanotubes: A Review
Photocatalytic ZnO based PES Membranes for AOP Water Treatments under UV and Sunlight
Plasma Activated Water as a Source of Nitrogen for Algae Growth
Digital Light Processing (DLP) 3D Printing of Polyethylene Glycol (PEG) Biopolymer, Commercially available Ultra-High and Tough (UHT) Resin and Maghemite (γ-Fe2O3) Nanoparticles Mixture for Tissue Engineering Scaffold Application
Fabrication of Nanoparticle Embedded Polymeric Microbeads as an Efficient Drug Delivery System
Micro/Nanostructured Papers from Bagasse Pulp Reinforced by Nanofibrillated Cellulose from different Agro-Waste Sources
Structural, Optical and Magnetic Properties of Pristine, (Mn, Al) co-doped ZnO Nanocrystallites Synthesized via co-Precipitation Method
Nanosecond Laser Surface Patterning of Ti6Al4V Bio-alloy for Improved Biological Performance
Synthesis of Cu2O/Ag Composite Nanocubes with Promising Photoluminescence and Photodegradation Activity over Methylene Blue Dye
Locally available Clays of Bangladesh as a Replacement of imported Clays for Ceramic Industries
Green Synthesis and Characterization of Silver Nanoparticles using Cassia auriculata Leaves Extract and Its Efficacy as A Potential Antibacterial and Cytotoxic Effect
_1572929082.jpg)
Copyright ©2010-2019 VBRI Press
Full Article