1Amity Institute of Nanotechnology, AMITY University, Noida (UP), India
2Amity Institute of Physiotherapy, AMITY University, Noida (UP), India
3Department of Biochemistry, M. D. University, Rohtak 124 001, Haryana, India
4Faculty of Pharmaceutical science PGIMS, Rohtak, India
Adv. Mater. Lett., 2015, 6 (3), pp 209-216
DOI: 10.5185/amlett.2015.5675
Publication Date (Web): Feb 22, 2015
Copyright © IAAM-VBRI Press
E-mail: jags_biotech@yahoo.co.in
A polyphenol oxidase (PPO) was immobilized by employing magnetic nanoparticles-zinc oxide/zinc hexacyanoferrate (Fe3O4NP-ZnO/ZnHCF) hybrid film electrodeposited on the surface of Pt electrode. The surface functionalization of Fe3O4NP-ZnO/ZnHCF hybrid film was characterized by cyclic voltammetry (CV), scanning electron microscopy (SEM), atomic force microscopy (AFM) and electrochemical impedance spectroscopy (EIS) before and after immobilization of PPO. The biosensor exhibited optimum response within 4s at pH 7.0 and 35°C and linearity in the range 0.04 to 10000 μM for acetaminophen with a detection limit of 0.04 μM (S/N=3). Accuracy of the proposed sensor was found to be 99%. The use of Fe3O4NP/ZnO/ZnOHCF for construction of amperometric acetaminophen biosensor has resulted into relatively rapid response, higher sensitivity, broad linear range, lower detection limit, good reproducibility and long term stability of this biosensor. This sensing interface provides better avenue for the fabrication of various sensor.
Drug monitoring, acetaminophen, magnetic nanoparticles, zinc oxide/zinc hexacyanoferrate film, Pt electrode.
Professor Prasad Yarlagadda’s Research Well Adopted as per needs of Engineering Industry
The Perspective of a Homogenization Approach for Effective Local and Non-local Response of the Elastic Wave Properties of Phononic Metamaterials
Reactor Cycling of Granulated Ca(OH)2 Encapsulated with Chemically Modified Semipermeable Shell Materials
Nanotoxicological Assessments to Warranty the use of Functionalized Y2O3 Nanoparticles for Biomedical Applications
Comparison of Photocatalytic Efficiency of TiO2 and In2S3 Thin Films under UV and Visible Light Irradiance
Application of Rice Husk Ash as Thermal Insulation Materials
Synthesis and Characterization of Green CuO using Centella Asiatica Plant Leaf Extract: Electrochemical and Photocatalytic Activities
Dielectric Relaxation and Suitability of Scaling parameters study on Mn0.7+xZn0.3SixFe2-2xO4 (x = 0.0 - 0.3) Ferrites
Synthesis and Screen Printing of Dopant Free Nano-crystalline SnO2 (101) Thick Film for Gas Sensor Application
Water and Sanitation Management: During and after COVID-19 Pandemic
Polymeric Energy Materials: Development and Challenges
Influence of Different Copolymer Based Compatibilizers on Performance of Pristine and Recycled PP/PE blends
Bio Ceramics: New Material from Mangrove Bark
Hybrid Physical Chemical Vapour Deposition (HPCVD) of Superconducting MgB2 Thin Films on three Dimensional Copper Substrates
Photoinduced Electron Transfer Reactions of tris(4,4’-dimethoxy-2,2’-bipyridyl)ruthenium(II)cation with Quinones in Aqueous Medium
A Comparative Study of Green Synthesized AgNPs using Carissa Carandas and Nerium indicum Leaves and its Activities against Selected Human Pathogens and MCF 7 Cell
Design and Modelling of Carbon Fiber Grid Structure based Carbon/Epoxy Composites for Enhanced Microwave Absorbing Properties
Elaboration and Characterization of Macroporous Bioceramics using Polymeric Sponge Replication Method
Copyright ©2010-2020 VBRI Press
Full Article