Preparation And Characterization Of Cellulose Derived From Rice Husk For Drug Delivery

¹Bhaskaracharya College of Applied Sciences, University of Delhi, Delhi110075, India

²Biosensors and Bioelectronics Centre, Institute of Physics, Chemistry and Biology (IFM), Linköping University, S-58183, Linköping, Sweden

Adv. Mater. Lett., 2013, Current Issue , 4 (9), pp 714-719

DOI: 10.5185/amlett.2013.2415

Publication Date (Web): Aug 10, 2013

Copyright © IAAM-VBRI Press

E-mail: sarojshukla2003@yahoo.co.in, ashutosh.tiwari@liu.se 

Abstract

Cellulose has been the extracted from rice husk by chemical treatment with aqueous solution of sodium hydroxide. The physical properties of derived cellulose (water uptake and swelling behavior) has been investigated with view of different applications. The morphology and chemical structure were investigated by Infrared spectroscopy (FT-IR), Scanning electron microscopy (SEM) and Thermogravimetry (TG) techniques. The results revealed the formation of homogeneous porous (micro size) membrane. Further, the UV-vis spectra of cellulose in different pH shows its responsiveness towards hydronium ion, which is suitable for drug delivery. Further, obtained cellulose was used for drug delivery under optimized pH.

Keywords

Rice husks, cellulose, pH responsiveness, drug delivery.