Cover Page September-2010-Advanced Materials Letters

Advanced Materials Letters

Volume 1, Issue 2, Pages 164-169, September 2010
About Cover

A High Throughput Chemiluminescence Method Based On Molecularly Imprinted Sol-gel Films For Determination Of Sibutramine

Fuwei Wan, Jinghua Yu*, Shenguang Ge, Mei Yan, Kexiao  Yu, Meng Zhang

Shandong Provincial Key Laboratory of Fluorine Chemistry and Chemical Materials, School of Chemistry and Chemical

Engineering, University of Jinan, Jinan 250022, China

Adv. Mater. Lett., 2010, 1 (2), pp 164-169

DOI: 10.5185/amlett.2010.7138

Publication Date (Web): Apr 08, 2012



A novel and high throughput chemiluminescence (CL) method for determination of sibutramine was originally developed based on potassium permanganate-hydrochloric acid-(tween-80) CL system. Molecularly imprinted sol-gel film (MIF) was synthesized and used as selective material to improve the selectivity of CL. In the proposed procedure, sibutramine molecule was adsorbed into the MIF, and then potassium permanganate, hydrochloric acid and tween-80 were added in wells of a 96-well plate, Based on which, sibutramine was oxidized and CL was produced and detected by a photomultiplier tube (PMT). The CL intensity was correlated linear with the concentration of sibutramine over the range of 5.0 × 10-8-1.0 × 10-6 g×mL-1  and the detection limit was 1.8 × 10-8 g×mL-1 . The relative standard deviation (RSD) was 3.1% for determination of 1.0 × 10-7 g×mL-1 sibutramine (n = 11). The fabricated molecularly imprinted sol-gel film possessed good selectivity and could be regenerated. This method was successfully applied to the determination of sibutramine in weight-reducing tonic.


Sibutramine, chemiluminescence, molecularly imprinted film, high throughput

Previous issues

Current Global Scenario of Electric Vehicles

Review on Detection of Phenol in Water 

Investigating the Machinability of Metallic Matrix Composites Reinforced by Carbon Nanotubes: A Review

Photocatalytic ZnO based PES Membranes for AOP Water Treatments under UV and Sunlight

Plasma Activated Water as a Source of Nitrogen for Algae Growth

Digital Light Processing (DLP) 3D Printing of Polyethylene Glycol (PEG) Biopolymer, Commercially available Ultra-High and Tough (UHT) Resin and Maghemite (γ-Fe2O3) Nanoparticles Mixture for Tissue Engineering Scaffold Application

Fabrication of Nanoparticle Embedded Polymeric Microbeads as an Efficient Drug Delivery System

Micro/Nanostructured Papers from Bagasse Pulp Reinforced by Nanofibrillated Cellulose from different Agro-Waste Sources

Structural, Optical and Magnetic Properties of Pristine, (Mn, Al) co-doped ZnO Nanocrystallites Synthesized via co-Precipitation Method

Nanosecond Laser Surface Patterning of Ti6Al4V Bio-alloy for Improved Biological Performance

Synthesis of Cu2O/Ag Composite Nanocubes with Promising Photoluminescence and Photodegradation Activity over Methylene Blue Dye

Locally available Clays of Bangladesh as a Replacement of imported Clays for Ceramic Industries 

Green Synthesis and Characterization of Silver Nanoparticles using Cassia auriculata Leaves Extract and Its Efficacy as A Potential Antibacterial and Cytotoxic Effect

Upcoming Congress

Knowledge Experience at Sea TM