Vilsmeier-Haack Transformations under Non Classical Conditions

Tasneem Mohammed1,*, Aejaz A. Khan1, S. M. Shakeel Iqubal1, Touseef Begum2

1Department of General Science, Ibn Sina National College for Medical Studies, Jeddah, Kingdom of Saudi Arabia
2Department of Pharmaceutical Science, Ibn Sina National College for Medical Studies, Jeddah, Kingdom of Saudi Arabia

Adv. Mater. Lett., 2020, 11 (2), 20021476

DOI: 10.5185/amlett.2020.021476

Publication Date (Web): Jan 27, 2020



Anisoles and Pyridines undergo acetylation and formylation under non-classical Vilsmeier-Haack conditions. The reactants are grinded vigorously in a mortar for about 25 to 30 min at room temperature with a pestle. The introduction of formyl and acetyl groups under solvent free conditions is a unique, fast and efficient method which has not been reported in literature so far.



Vilsmeier-Haack reaction, anisoles, pyridines, dimethylformamide, dimethylacetamide.

Previous issues

Celebrating 10th Years of Diamond Open Access Publishing in Advanced Materials  

Cerebral Oxygenation Studies Through Near Infrared Spectroscopy: A Review

Analysis of Fine Sulfoaluminate Cement by Strength and Thermogravimetric Analysis

Characterization of the Interfacial Surface Energy for Composite Electrical Conduction Measurements using Two Full Range Percolation Threshold Models

Quantitative Detect of Fatigue of Membrane of Erythrocyte in Uniform Shear Field

Ecofriendly-developed Polyacrylic Acid-coated Magnetic Nanoparticles as Catalysts in Photo-fenton Processes

Evaluation of Drug Interactions with Medications Prescribed to Ambulatory Patients with Metabolic Syndrome in Urban Area

Fiber-reinforced Cementitious Composite: Sensitivity Analysis and Parameter Identification 

Evaluation of Drug Utilization Patterns Based on World Health Organization Drug use Indicators at Outpatients Clinics

Are Quantitatively Micro-machined Scaffolds Effective for Cell Technology?

Synthesis and Characterization of Gold Nanoparticles from Lobelia Nicotianifolia Leaf Extract and its Biological Activities

Advanced Oxidations of Tartrazine Azo-dye

Antifungal Activity of Salvia jordanii Against the Oral Thrush Caused by the Cosmopolitan Yeast Candida albicans among Elderly Diabetic Type 2 patients

Upcoming Congress

Knowledge Experience at Sea TM