Green fabrication of zinc oxide nanospheres by aspidopterys cordata for effective antioxidant and antibacterial activity

Prashant B. Chouke1, 2, Ajay K. Potbhare1, Ganesh S. Bhusari3, Subhash Somkuwar4, Dadamia PMD Shaik5, Raghvendra K. Mishra6, Ratiram Gomaji Chaudhary1*

1Post-Graduate Department of Chemistry, Seth Kesarimal Porwal College, Kamptee, Maharashtra 441 001, India

2Department of Chemistry, Government Polytechnic, Bramhapuri, Maharashtra 441206, India

3Research and Development Division, Apple Chemie India Private Limited, Nagpur, Maharashtra 440 015, India

4Department of Botany, Dr. Babasaheb Ambedkar College, Nagpur, Maharashtra 440 010, India

5Department of Physics, Sree Vidhyaniketan Engineering College, Tirupati, Andhra Pradesh 517 102, India

6International Interuniversity Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam (Kerala) 686560, India

DOI: 10.5185/amlett.2019.2235

Publication Date (Web): Jan 14, 2019



The present work portray the Aspidopterys Cordata (AC) leaf extract-assisted fabrication of zinc oxide nanospheres (ZnO NSs) using an eco-friendly approach for antibacterial and antioxidant activity. As fabricated ZnO NSs were characterized by X-ray diffraction (XRD), Fourier transform infrared (FT-IR), energy dispersive X-ray diffraction (EDX), UV-Visible diffuse reflectance spectroscopy (UV-DRS), Raman, X-ray photoelectron spectroscopy (XPS), scanning electron microscope (SEM), and transmission electron microscope (TEM) for authenticate the structure, shape, size, chemical state, and morphological facet. XRD pattern showed the strong and intense diffraction peaks indicating the formation of crystalline ZnO NSs with hexagonal phase. Further, EDX revealed the formation of highly pure ZnO with signals of Zn and O elements. UV–DRS reveals absorption band at 370 nm, assigned to the intrinsic band-gap absorption of ZnO, owing to the electron transitions from valence band to conduction band. TEM images inveterate the formations of ZnO NSs with mean particle size of 11.6 nm. The antibacterial activity of ZnO NSs was examined against gram-positive (Staphylococcus aureus) and gram-negative (Proteus vulgaris, Escherichia coli, and Klebsiella pneumonia) human pathogenic bacteria using ZnO NSs by agar-well diffusion method. Furthermore, ZnO NSs exhibited significant antioxidant activity against scavenging 1, 1-Diphenyl-2-picrylhydrazyl (DPPH) free radicals.


ZnO nanospheres, aspidopterys cordata, electron spectroscopy, antioxidant activity, antibacterial assay.

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