Preparation of novel tragacanth gum-entrapped lecithin nanogels 

Chetna Verma1, 4, Poonam Negi2, Deepak Pathania3, Sadiya Anjum4, Bhuvanesh Gupta4*

1Department of Chemistry, Shoolini University, Solan, Himachal Pradesh 173229, India

2Department of Pharmacy, Shoolini University, Solan, Himachal Pradesh 173229, India

3Department of Environmental Science, Central University of Jammu, Jammu and Kashmir 181143, India

4Bioengineering Laboratory, Department of Textile Technology, Indian Institute of Technology, New Delhi 110016, India

DOI: 10.5185/amlett.2019.2207

Publication Date (Web): Jan 10, 2019

E-mail: bgupta@textile.iitd.ernet.in, poonam.garge@gmail.com

Abstract

Nanogel synthesis is gaining enormous interest in a large number of applications, such as drug delivery, wound care systems and tissue engineering. In the present work, we have investigated the preparation of Tragacanth gum (TG) nanoparticles in a water-in-oil nanoemulsion system. These nanoparticles exhibit stacked core-shell type of structure in which polygonal TG nanoparticles are covered by lipid structured lecithin (LC). The resultant nanoparticles comprise of amphillic nature, i.e. the hydrophilic TG core and hydrophobic LC shell which offers interesting features of immobilization of biomolecules.

Keywords

Tragacanth gum, lecithin, dioctylsulfosuccinate sodium salt, nanoemulsion, surfactant.

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