Preparation of novel tragacanth gum-entrapped lecithin nanogels 

¹Department of Chemistry, Shoolini University, Solan, Himachal Pradesh 173229, India

²Department of Pharmacy, Shoolini University, Solan, Himachal Pradesh 173229, India

³Department of Environmental Science, Central University of Jammu, Jammu and Kashmir 181143, India

⁴Bioengineering Laboratory, Department of Textile Technology, Indian Institute of Technology, New Delhi 110016, India

Adv. Mater. Lett., 2019, 10 (4), pp 267-269

DOI: 10.5185/amlett.2019.2207

Publication Date (Web): Jan 10, 2019

Copyright © IAAM-VBRI Press

E-mail: bgupta@textile.iitd.ernet.in, poonam.garge@gmail.com

Abstract

Nanogel synthesis is gaining enormous interest in a large number of applications, such as drug delivery, wound care systems and tissue engineering. In the present work, we have investigated the preparation of Tragacanth gum (TG) nanoparticles in a water-in-oil nanoemulsion system. These nanoparticles exhibit stacked core-shell type of structure in which polygonal TG nanoparticles are covered by lipid structured lecithin (LC). The resultant nanoparticles comprise of amphillic nature, i.e. the hydrophilic TG core and hydrophobic LC shell which offers interesting features of immobilization of biomolecules.

Keywords

Tragacanth gum, lecithin, dioctylsulfosuccinate sodium salt, nanoemulsion, surfactant.