Cover Page November-2018-Advanced Materials Letters

Advanced Materials Letters

Volume 9, Issue 11, Pages 748-752, November 2018
About Cover

Cover page describe the Typical fracture surface of nuclear graphite blocks after irradiation (cracks occur during reactor operation). This picture Summarize the Fractographic studies of GR-280 nuclear graphite after irradiation up to neutron fluence above the turnaround dose (with a decrease in of the mechanical properties to the values close to the initial one after primary radiation-induced increase) showed along with the presence of transcrystalline fracture, appearance of intercrystalline fracture regions along the “filler-binder” type boundaries.


Multilayer ceramics as integration platform for sensors in in-vitro cell culture reactors

Heike Bartsch1*, Martin Baca2, Uta Fernekorn2, Marcel Himmerlich3, Jens Müller1, Andreas Schober2, Hartmut Witte4

Technische Universität Ilmenau, IMN MacroNano®, Ilmenau, 98693, Germany

1Electronics Technology Group
2Nano-Biosystems Technology Group 
3Technical Physicist Group
4Biomechatronics Group​

Adv. Mater. Lett., 2018, 9 (11), pp 748-752

DOI: 10.5185/amlett.2018.2090

Publication Date (Web): Jul 24, 2018

E-mail: heike.bartsch@tu-ilmenau.de

Abstract

Monitoring systems that are capable to record neuronal activity in in-vitro cell cultures are prerequisite to the comprehensive investigation of neuronal processes. Low temperature cofired ceramics are a suitable platform for rapid prototyping of biological reactors, entailing a wide assortment of integration-capable sensors. Neuronal spikes capture is fundamental for understanding of the signal propagation within the neuronal network. It requires reliable electrodes, which can be arranged 3-dimensionally in an in vitro cell culture. Thick film gold electrodes have been proven for such applications, however their characteristics especially at small dimensions stray strongly. This work investigates thin films separating small thick film gold electrodes and an electrolyte solution with regard to their influence on the charge transport processes in such systems. PEDOT:PSS layer and TiOxNy deposited on LTCC gold electrodes, including their impedance characteristics are discussed and compared. TiOxNy layers with serial resistance Rs of 32 kΩ and serial capacitance Cs of 4.1 pF measured at 1 kHz are proposed to be the used as sensing elements in 3-dimensional in vitro cell cultures.                                                                       

Keywords

Bio-reactors, low temperature co-fired ceramics, LTCC, thick film technology, sensor integration.

Current Issue

9th Anniversary of Advanced Materials Letters: Progress and Opportunities


Coating - A potent method to enhance electrochemical performance of Li(NixMnyCoz)O2 cathodes for Li-ion batteries


Analysis of machined electron beam treated Ti6Al4V-ELI implant surfaces


Bottom-up design of hydrogels through click-chemistry modification of magnetic nanoparticles


Visualization of mechanical loads with semiconductor nanocrystals 


Room temperature growth of ultra porous hot-wire deposited tantalum pentoxide


Substrate integrated circular cavity resonator filled with nano-fibrillated cellulose for humidity detection


Oxygen vacancy filament-based resistive switching in Hf0.5Zr0.5O2 thin films for non-volatile memory


Innovative silicon compatible materials for light emitting devices  


Graphene micromesh for transparent conductive films application 


Applications of nano-scale Cirrus DopantTM to improve existing coatings


Chitin nanofibrils in renewable materials for packaging and personal care applications


Synthesis of AgNPs embedded double network nanocomposite hydrogels having high swelling and anti-bacterial characteristics


Previous issues

Artificial intelligence and machine learning empowering the mass medicine

Piezo-therapy in cancer: Current research and perspectives

Magnetic microwires for sensor applications

A fundamental study on the mechanistic impact of repeated de- and rehydration of Ca(OH)2 on thermochemical cycling in technical scale

Fabrication and characterization of nano-bridge Josephson junction based on Fe0.94Te0.45Se0.55 thin film

Riboflavin-UVA gelatin crosslinking: Design of a biocompatible and thermo-responsive biomaterial with enhanced mechanical properties for tissue engineering

Broadband and fast photodetectors based on multilayer p-MoTe2/n-WS2 heterojunction with graphene electrodes

Ionic liquid [BMIM][Cl] immobilized on cellulose fibers from pineapple leaves for desulphurization of fuels

Synthesis and role of co-dopants (alkaline earth divalents and halides) on the photoluminescence of Eu2+ doped BaAl2O4 phosphor

Metal oxide (V2O5) incorporated fly ash based geopolymer for better sustainable engineering composites

Highly efficient storage of solar gains using aluminum foam heat exchangers  

Green fabrication of zinc oxide nanospheres by aspidopterys cordata for effective antioxidant and antibacterial activity

Effect of diamantane on the thermal stability of cryomilled aluminum alloy

Upcoming Congress

Knowledge Experience at Sea TM