The cover describes the development of nanofibers with encapsulated growth factors has been emerged as a promising approach in neo-tissues applications. The proposed nanofibrous systems provide a novel approach to both simulate the extra-cellular matrix for cell adhesion and also for localized delivery of signaling molecules and growth factors. Growth factors could be loaded into nanofibers using different techniques including physical adsorption, covalent bonding or encapsulation.
Radiation engineered copper nanoparticles immobilised catalytic reactor (Cu-NICaR) system
Swarnima Rawat1, Nilanjal Misra1, Virendra Kumar1, 2*, Shubhangi Atmaram Shelkar1, Narender Kumar Goel1, Rakesh Kumar Singhal3, Lalit Varshney1, 2
1Radiation Technology Development Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India
2Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, India
3Analytical Chemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India
Adv. Mater. Lett., 2018, 9 (10), pp 684-691
Publication Date (Web): Jul 18, 2018
Copyright © 2019 VBRI Press
A robust and reusable Copper Nanoparticles Immobilised Catalytic Reactor (Cu-NICaR) system was fabricated by immobilising Copper Nanoparticles (Cu NPs) onto a radiation functionalized polymer support. Gamma radiation induced simultaneous irradiation grafting process was employed for introducing poly-glycidyl methacrylate (poly(GMA)) chains onto non woven PE-PP matrix. Optimization of the grafting process was carried out by studying the effect of experimental parameters, such as absorbed dose, monomer concentration and solvent polarity on grafting yield. The poly(GMA)-g-PE-PP matrix was used as a functional polymer support for Cu NPs, synthesised under optimized conditions using NaBH4 as reducing agent. Characterization of the samples was carried out by UV-Visible spectrophotometer, Fourier Transform Infrared (FTIR) Spectroscopy, X-ray fluorescence (XRF), Thermogravimetric Analysis (TGA) and Scanning Electron Microscopy (SEM). Catalytic activity of Cu NPs immobilised poly(GMA)-g-PE-PP catalytic system was studied by spectrophotometrically monitoring the catalytic reduction of p-nitrophenol (PNP), using NaBH4 as reducing agent. The Cu NPs-immobilised-poly(GMA)-g-PE-PP was observed to exhibit excellent catalytic activity both in batch process (12 cycles over a period of 30 days) as well as in fixed bed column reactor mode, without significant loss of activity.
Radiation grafting, copper nanoparticles, Cu-NICaR, catalyst, p-nitrophenol.