Graphenated ceramic nanofibers for highly sensitive simultaneous detection of dopamine, uric acid and ascorbic acid

¹Tallinn University of Technology, Department of Materials Engineering, Ehitajate 5, Tallinn, Estonia

²ITMO University, Kronverksky 49, St. Petersburg, Russian Federation

³University of Illinois at Urbana-Champaign, Department of Mechanical Science and Engineering, Urbana, IL 61801, USA

Adv. Mater. Lett., 2017, 8 (12), pp 1178-1183

DOI: 10.5185/amlett.2017.1557

Publication Date (Web): Sep 08, 2017

Copyright © IAAM-VBRI Press

E-mail: irina.hussainova@ttu.ee

Abstract

The present study reports the simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA) in 0.1 M phosphate buffer solution (pH = 7.0) using a novel electrode material prepared from oxide ceramic nanofibers by applying a single step chemical vapor deposition method. Electron-transfer kinetics at the electrode/solution interface was studied by standard redox reaction of 5 mM Fe(CN)₆^3-/4- in 1 M KCl. Electrochemical and sensing measurements such as cyclic voltammetry and differential pulse voltammetry were performed to detect DA and UA in the presence of AA. The developed electrode was shown to separate the overlapping voltammetric responses of three analytes into the individual voltammetric peaks, totally eliminate the interference from AA, and distinguish DA from UA. Linear relationship was observed between current intensities and concentrations of all three compounds, and the limits of detection (LOD) were reached 0.57 µM, 0.77 µM and 0.84 µM for DA, UA and AA, respectively. The electrode of graphenated nanofibers displayed a very good reproducibility and stability, and was successfully tested for detection of DA, UA and AA in real urine samples. 

Keywords

Graphene, ascorbic acid, dopamine, uric acid, voltammetry.