Increasing the metal loading in passion fruit-like nano-architectures

Rosa D’Apice, Valerio Voliani*

Center for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia, P.zza San Silvestro, 12 – 56126 - Pisa (PI), Italy

Adv. Mater. Lett., 2017, 8 (12), pp 1156-1160

DOI: 10.5185/amlett.2017.1668

Publication Date (Web): Sep 08, 2017

Abstract


Noble metal nanostructures have demonstrated many intriguing features for both therapy and diagnosis in a number of diseases. However, their clinical translation is prevented by their accumulation in organisms that can result in toxicity and interference with common medical diagnoses. In order to combine the most interesting behaviour of metal nanoparticles with the possibility of their body clearance, we have recently introduced and tested the passion fruit-like nano-architectures. They are versatile 100 nm biodegradable nanostructures composed by a silica shell embedding functional polymeric arrays of ultra-small noble metal nanoparticles. Here, we report a novel simple and robust protocol to increase the loading of ultra small gold nanoparticles in the nano-architectures, promoting their possible application in clinical diagnosis. 

Keywords

Metal nanoparticles, biodegradable, nanomedicine, drug delivery, diagnosis, silica.

Previous issues

Celebrating 10th Years of Diamond Open Access Publishing in Advanced Materials  

Cerebral Oxygenation Studies Through Near Infrared Spectroscopy: A Review

Analysis of Fine Sulfoaluminate Cement by Strength and Thermogravimetric Analysis

Characterization of the Interfacial Surface Energy for Composite Electrical Conduction Measurements using Two Full Range Percolation Threshold Models

Quantitative Detect of Fatigue of Membrane of Erythrocyte in Uniform Shear Field

Ecofriendly-developed Polyacrylic Acid-coated Magnetic Nanoparticles as Catalysts in Photo-fenton Processes

Evaluation of Drug Interactions with Medications Prescribed to Ambulatory Patients with Metabolic Syndrome in Urban Area

Fiber-reinforced Cementitious Composite: Sensitivity Analysis and Parameter Identification 

Evaluation of Drug Utilization Patterns Based on World Health Organization Drug use Indicators at Outpatients Clinics

Are Quantitatively Micro-machined Scaffolds Effective for Cell Technology?

Synthesis and Characterization of Gold Nanoparticles from Lobelia Nicotianifolia Leaf Extract and its Biological Activities

Advanced Oxidations of Tartrazine Azo-dye

Antifungal Activity of Salvia jordanii Against the Oral Thrush Caused by the Cosmopolitan Yeast Candida albicans among Elderly Diabetic Type 2 patients

Upcoming Congress

Knowledge Experience at Sea TM