Adv. Mater. Lett., 2011, 2 (2), pp 90-99
DOI: 10.5185/amlett.2011.1211
Publication Date (Web): Apr 08, 2012
Copyright © IAAM-VBRI Press
Cartilage is an avascular connective tissue found in many locations in the body, such as, in the joints between the bones, rib cage, ear, nose and intervertebral discs. Cartilage plays a vital role in our body by working as a cushion between joints so that rubbing of bones against each other is prevented. It also holds some bones together, for instance, rib cartilage, and makes the area shock-proof. Cartilage is composed of single type of cells called chondrocytes. There are several diseases associated with cartilage, e.g., osteoarthritis, traumatic rupture of cartilage. These defects are not easy to repair as cartilage possesses limited self repair capacity due to the lack of a sufficient supply of healthy chondrocytes to the defective sites. Tissue engineered cartilage can serve as a lifelong treatment to such problems. Reconstruction of the cartilage can be achieved by use of appropriate cell source, scaffold, and growth factors. Development of a 3D cartilaginous skeleton have challenged the researchers for decades as the pursuit for suitable cell source, biomaterials and growth factor combination is not yet over. Various composite biomaterials and multiple growth factor approach are applied nowadays to regenerate cartilage. Stem cell has emerged as a potent source of cells for cartilage regeneration. This review highlightens the advances in cartilage tissue engineering by throwing light on cell sources, scaffold materials as well as on growth factors used so far in cartilage tissue engineering. It also reflects a range of problems and future perspectives to overcome the existing hurdles in cartilage regeneration. © 2011 VBRI press.
Adaptations and Lessons from COVID-19: A Perspective on How some Industries will be Impacted
Background and Strategies for Identification and Design of Materials for Thermochemical Energy Storage and Conversion
Phosphorus Gasification during the Reduction of basic Oxygen Furnace Slags in a Novel Reactor Concept
Concrete Electrical Resistivity at Varied Water, Chloride Contents and Porosity – Experiment, Modelling & Application
Water Purifying Bio-concrete
Local Fluctuations of Transformation to “Amorphous Diamond” from C60 Fullerenes and Neutron-irradiated Graphite under Shock-compression
Coulomb Drag of Electron-Electron Interactions in GaAs Bilayer with a Non Homogeneous Dielectric Background
Effect of Nd-concentration in Nd(2-x)FexO3 System on the Crystal Structure and Microwave Absorption Characteristics
Experimental Study on Strength Characteristics of Chopped Glass Fiber (CGF) Cement-Mortar Composites
Researcher of the Year 2020: Professor Herbert Gleiter, Germany
Self-sealing Polymeric Materials: Mechanism and Applications
Development of Ruthenium Complex Based Sensitizers, Organic Based Sensitizers, and Co-sensitization System for Dye-sensitized Solar Cells
Characterization of a New Copper Paste for Printed Electronics
Co-Ni Nanowires Arrays with Tunable Properties Obtained by Template Synthesis
Dispersion of Multi-Walled Carbon Nanotubes Using Polyvinylpyrrolidone for Application in Cement - Based Composites to Enhance Electrical Conductivity
Towards a Physics Based Model of Magnetic Barkhausen Noise in Steel
Sustainable Concept and Economic Evaluation of a Solar-Powered Hydrogen Generation Unit
Macrocell Corrosion and its Countermeasure for Reinforced Concrete after Patch Repair
Modelling the Height of Hydrothermally Synthesized Titanium Dioxide Nanostructures
Cellular SiC/Iron Alloy Composite
Conceptual Design of the CSP Lead Demonstrator SOLEAD
Numerical and Experimental Analyses of Equal Channel Angular Processing of Pure Aluminum
Copyright ©2010-2020 VBRI Press
Full Article