Cartilage Tissue Engineering: Current Scenario And Challenges
Adv. Mater. Lett., 2011, 2 (2), pp 90-99
DOI: 10.5185/amlett.2011.1211
Publication Date (Web): Apr 08, 2012
Copyright © 2019 VBRI Press
Cartilage is an avascular connective tissue found in many locations in the body, such as, in the joints between the bones, rib cage, ear, nose and intervertebral discs. Cartilage plays a vital role in our body by working as a cushion between joints so that rubbing of bones against each other is prevented. It also holds some bones together, for instance, rib cartilage, and makes the area shock-proof. Cartilage is composed of single type of cells called chondrocytes. There are several diseases associated with cartilage, e.g., osteoarthritis, traumatic rupture of cartilage. These defects are not easy to repair as cartilage possesses limited self repair capacity due to the lack of a sufficient supply of healthy chondrocytes to the defective sites. Tissue engineered cartilage can serve as a lifelong treatment to such problems. Reconstruction of the cartilage can be achieved by use of appropriate cell source, scaffold, and growth factors. Development of a 3D cartilaginous skeleton have challenged the researchers for decades as the pursuit for suitable cell source, biomaterials and growth factor combination is not yet over. Various composite biomaterials and multiple growth factor approach are applied nowadays to regenerate cartilage. Stem cell has emerged as a potent source of cells for cartilage regeneration. This review highlightens the advances in cartilage tissue engineering by throwing light on cell sources, scaffold materials as well as on growth factors used so far in cartilage tissue engineering. It also reflects a range of problems and future perspectives to overcome the existing hurdles in cartilage regeneration. © 2011 VBRI press.
Healthcare informatics driven nanotechnology
Brief Review: Simulation of Novel Systems Using Duality Quantum Algorithm
Significant Quality Parameters of Finishing Technology in Offset Printing on Solid Board Boxes Depending on the type of Material
Generation of entanglement in spin states of Rydberg atoms by chirped optical pulses
Matrix and Variant Transformations Simulate Statistical Canonical Ensembles from Fock to Poissonian States of Random Sequences
The Vortex Glass-Liquid Transition in Fe1.02Se Crystal
Magnetic Properties of Intercalated Gr/Ni (111) System
Functionalized Nano Carbon for excellent Microwave Absorption at GHz Frequency
Deformation Texture Modelling by Mean-Field and Full-Field Approaches
Growth, Linear and Nonlinear Optical Studies of D-Tartaric Acid Crystal
Graphene-MoS2-Au-TiO2-SiO2 Hybrid SPR Biosensor for Formalin Detection: Numerical Analysis and Development
Microstructure and Mechanical Characterization Study in the IN718/BNi-2/316L Joint by Transient Liquid Phase Bonding Process
Stress Fields at the Central Point of Arc Crack under Uniaxial Tension
Cloud Medicine set to Revolutionize Doorstep Personalized Healthcare
Various surfactants for 0 – 3 dimensional nanocarbons: Separation, exfoliation and solubilization
Polypyrrole based biofunctional composite layer for bioelectrocatalytic device system
Innovative Graphene-PDMS sensors for aerospace applications
Effect of hot drawing process and carbonization temperature in electrochemical behavior of electrospun carbon nanofibers
Chemical Reactivity and Electronical Properties of Graphene and Reduced Graphene Oxide on Different Substrates
Laser Raman micro-spectroscopy as an effective non-destructive method of detection and identification of various sp2 carbon modifications in industry and in nature
Electrochemical promotion of ammonia synthesis with proton-conducting solid oxide fuel cells
Biomimetic surfaces with hierarchical structure using microsized texture and nanosized Cu particles for superhydrophobicity
Enhancement the properties of high and low-density polyethylene membranes by radiation grafting process
Synthesis of 9-Aminoacridine and its Application as an Anode Material for Aqueous Rechargeable Lithium–ion Batteries
Facile synthesis of novel tough and highly flexible biodegradable membranes for water microfiltration
Investigating the possibility of using acetic acid in place of HF in chromium-benzenedicarboxylates (MIL-53 and MIL-101) synthesis applicable for CO2 adsorption
Copyright ©2010-2019 VBRI Press
Full Article