Cover Page June-2011-Advanced Materials Letters

Advanced Materials Letters

Volume 2, Issue 2, Pages 90-99, June 2011
About Cover


Cartilage Tissue Engineering: Current Scenario And Challenges

Chhavi Sharma, Sneh Gautam, Amit K. Dinda, Narayan C. Mishra

Adv. Mater. Lett., 2011, 2 (2), pp 90-99

DOI: 10.5185/amlett.2011.1211

Publication Date (Web): Apr 08, 2012

Abstract

Cartilage is an avascular connective tissue found in many locations in the body, such as, in the joints between the bones, rib cage, ear, nose and intervertebral discs. Cartilage plays a vital role in our body by working as a cushion between joints so that rubbing of bones against each other is prevented. It also holds some bones together, for instance, rib cartilage, and makes the area shock-proof. Cartilage is composed of single type of cells called chondrocytes. There are several diseases associated with cartilage, e.g., osteoarthritis, traumatic rupture of cartilage. These defects are not easy to repair as cartilage possesses limited self repair capacity due to the lack of a sufficient supply of healthy chondrocytes to the defective sites. Tissue engineered cartilage can serve as a lifelong treatment to such problems. Reconstruction of the cartilage can be achieved by use of appropriate cell source, scaffold, and growth factors. Development of a 3D cartilaginous skeleton have challenged the researchers for decades as the pursuit for suitable cell source, biomaterials and growth factor combination is not yet over. Various composite biomaterials and multiple growth factor approach are applied nowadays to regenerate cartilage. Stem cell has emerged as a potent source of cells for cartilage regeneration. This review highlightens the advances in cartilage tissue engineering by throwing light on cell sources, scaffold materials as well as on growth factors used so far in cartilage tissue engineering. It also reflects a range of problems and future perspectives to overcome the existing hurdles in cartilage regeneration. © 2011 VBRI press.

Keywords

Cartilage, chondrocytes, tissue engineering, biomaterials

Previous issues

Current Global Scenario of Electric Vehicles

Review on Detection of Phenol in Water 

Investigating the Machinability of Metallic Matrix Composites Reinforced by Carbon Nanotubes: A Review

Photocatalytic ZnO based PES Membranes for AOP Water Treatments under UV and Sunlight

Plasma Activated Water as a Source of Nitrogen for Algae Growth

Digital Light Processing (DLP) 3D Printing of Polyethylene Glycol (PEG) Biopolymer, Commercially available Ultra-High and Tough (UHT) Resin and Maghemite (γ-Fe2O3) Nanoparticles Mixture for Tissue Engineering Scaffold Application

Fabrication of Nanoparticle Embedded Polymeric Microbeads as an Efficient Drug Delivery System

Micro/Nanostructured Papers from Bagasse Pulp Reinforced by Nanofibrillated Cellulose from different Agro-Waste Sources

Structural, Optical and Magnetic Properties of Pristine, (Mn, Al) co-doped ZnO Nanocrystallites Synthesized via co-Precipitation Method

Nanosecond Laser Surface Patterning of Ti6Al4V Bio-alloy for Improved Biological Performance

Synthesis of Cu2O/Ag Composite Nanocubes with Promising Photoluminescence and Photodegradation Activity over Methylene Blue Dye

Locally available Clays of Bangladesh as a Replacement of imported Clays for Ceramic Industries 

Green Synthesis and Characterization of Silver Nanoparticles using Cassia auriculata Leaves Extract and Its Efficacy as A Potential Antibacterial and Cytotoxic Effect

Upcoming Congress

Knowledge Experience at Sea TM