Electrochemcial sensing of anti-diabetic drug using hierarchically deposited PB nanocubes on carbon nanospheres layered on transparent glass electrode

Jagriti Narang1*, Chaitali Singhal1, Vibhor Kaushal2, C. S. Pundir3

1Amity Institute of Nanotechnology, Amity University, Noida (UP), 201301, India

2Skinic, Agra (UP), 282002, India

3Department of Biochemistry, M. D. University, Rohtak 124 001, Haryana, India

Adv. Mater. Lett., 2017, 8 (4), pp 572-576

DOI: 10.5185/amlett.2017.7041

Publication Date (Web): Mar 15, 2017

E-mail: jags_biotech@yahoo.co.in

Abstract


Prussian Blue nanocubes / carbon nanospheres (PB-CNS) heterostructure composed of perfectly cube and spherical composite on indium tin oxide (ITO) surface were developed for in vitro sensing of anti-diabetic drug i.e. Sitagliptin (STA). Detailed morphological, electrochemical, structural and optical characterization of PB-CNS/ITO electrode was done using DLS, SEM, EIS, CV. The sensor showed rapid response time (within 5 s) and the linear range from 0.001 to 10 mM with a shelf life of about 10 weeks under refrigerated conditions. We have also attempted to employ this electrode for assessment of STA in urine samples. The developed sensor exhibited high reproducibility and good storage stability.

Keywords

Sitagliptin, prussian blue nanocubes, carbon nanospheres, sensor, ITO electrode.

Previous issues

Celebrating 10th Years of Diamond Open Access Publishing in Advanced Materials  

Cerebral Oxygenation Studies Through Near Infrared Spectroscopy: A Review

Analysis of Fine Sulfoaluminate Cement by Strength and Thermogravimetric Analysis

Characterization of the Interfacial Surface Energy for Composite Electrical Conduction Measurements using Two Full Range Percolation Threshold Models

Quantitative Detect of Fatigue of Membrane of Erythrocyte in Uniform Shear Field

Ecofriendly-developed Polyacrylic Acid-coated Magnetic Nanoparticles as Catalysts in Photo-fenton Processes

Evaluation of Drug Interactions with Medications Prescribed to Ambulatory Patients with Metabolic Syndrome in Urban Area

Fiber-reinforced Cementitious Composite: Sensitivity Analysis and Parameter Identification 

Evaluation of Drug Utilization Patterns Based on World Health Organization Drug use Indicators at Outpatients Clinics

Are Quantitatively Micro-machined Scaffolds Effective for Cell Technology?

Synthesis and Characterization of Gold Nanoparticles from Lobelia Nicotianifolia Leaf Extract and its Biological Activities

Advanced Oxidations of Tartrazine Azo-dye

Antifungal Activity of Salvia jordanii Against the Oral Thrush Caused by the Cosmopolitan Yeast Candida albicans among Elderly Diabetic Type 2 patients

Upcoming Congress

Knowledge Experience at Sea TM