Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China
Adv. Mater. Lett., 2017, 8 (3), pp 309-314
DOI: 10.5185/amlett.2017.7103
Publication Date (Web): Jan 28, 2017
Copyright © IAAM-VBRI Press
E-mail: zcwag@xmu.edu.cn
The flexible and freestanding graphene oxide (GO) film was fabricated for drug delivery and antibacterial. The film was synthesized by covalently attaching cefalexin onto graphene oxide sheets and then made by filtration of the colloidal suspension. SEM and optical images show that the Cefalexin-grafted graphene oxide (GO-CE) film possesses the unique 2D layer-by-layer structure and it could form channels for drug release when immersed in water. The drug loading and release tests certify that the GO-CE film is a promising drug delivery membrane with high load capacity (0.621 mg mg-1) and long-acting release properties (72 h), and can effectively inhibit the growth of E. coli and S. aureus bacteria while showing minimal cytotoxicity for a long time. The cellular culture results of the HeLa Cells indicate that the GO-CE film exhibits excellent biocompatibility. Based on these advantages, the GO-CE film is expected to be used in the environmental and medical applications.
Advanced Materials Research and Innovation Priorities for Accomplishing the Sustainable Development Goals
Contemporary Advances in Humidity Sensing Materials, Methods, and Performances
Roles of the Debye Length and Skin Depth in the Characterization of Space Charge Interactions in Semiconductor Nanoparticles
Antifungal Activity of Iron-gold and Cobalt-gold co-doped ZnO Nanoparticles
Adsorption and Thermodynamic Parameters of Activated Carbon-Diazepam Systems in Simulated Gastric Fluid
Synthesis, Impedance and Current-Voltage Spectroscopic Characterization of Novel Gadolinium Titanate Nano Structures
Removal of Toxic Dyes from Industrial Waste Water using Chitosan Grafted Itaconic Acid Nanocomposites
Structural, Optical and dielectric properties of Sr doped LaVO4
Design, 3D Development and Finite Element Analysis of Cylindrical Mesh Cage Bioimplants from Biometals
Advancements in Materials Technology for Accomplishing Sustainable Development Goals
A Review for Luminescence Property of Materials, Its Detection and Probabilities for Embedding of Luminescence with MEMS Technology
A Review on Low-Cost Adsorbents for Cadmium Pollutant Removal from Industrial Effluents
Study of Applications of Radial Basis Function Network in Forecasting
Simulation of LPG Pressure Vessel under Fire Engulfment
Strength Analysis of Friction Stir Welding (FSW) Joint Under Minimize Rotation Speed of FSW Tool
Formation of Pure In2O3 pallets for OLED Application
Study of Soil Nitrogen Level and Splitting on Nutrient Uptake around the Industries of Chhattisgarh, India
Copyright ©2010-2021 VBRI Press
Full Article