In Vitro Antibacterial And Anticancer Studies Of ZnO Nanoparticles Prepared By Sugar Fueled Combustion Synthesis
1Department of Chemistry, Sir M. Visvesvaraya Institute of Technology, Bengaluru 562157, India
2Research and Development Center, Bharathiar University, Coimbatore 641046, India
3Department of Chemistry, Sai Vidya Institute of Technology, Bengaluru 560 064, India
4Department of Bioscience and Bioengineering, Indian Institute of Technology, Guwahati 781039, India
5Department of Chemistry, M. S. Ramaiah Institute of Technology, Bengaluru 560054, India
Adv. Mater. Lett., 2017, 8 (1), pp 24-29
Publication Date (Web): Nov 12, 2016
Copyright © IAAM-VBRI Press
In this study, we report the antibacterial and anticancer activity of ZnO nanoparticles (NPs) prepared by sugar-fueled solution combustion synthesis. The structure and morphology of the sample were determined by XRD, UV-visible, FESEM and HRTEM. Surface area measurement was carried out by standard Brunauer-Emmett-Teller technique. Antibacterial activity of ZnO NPs was tested against Clostridium perfringens and Salmonella enterica by well diffusion method. The anticancer efficacy of ZnO nanoparticles was carried out on breast cancer cells MCF-7. The antibacterial results affirm that spherical ZnO NPs constitute as a successful bactericidal agent against both Gram-positive and Gram-negative bacteria. Anticancer result indicates that ZnO NPs exert dose dependent toxicity in MCF-7.
Combustion synthesis, clostridium perfringens, salmonella enterica, MCF-7, MTT assay.