Cover Page March-2015-Advanced Materials Letters

Advanced Materials Letters

Volume 6, Issue 3, Pages 235-241, March 2015
About Cover


Evaluation Of Antioxidant And Antibacterial Activity Of Various Aspect Ratio Gold (Au) Nanorods

Shyamalima Sharma1, Ajay Kumar Manhar2, Pritom Jyoti Bora3, Swapan Kumar Dolui1*, Manabendra Mandal

1Department of Chemical Sciences, Tezpur University, Napaam, Tezpur, Assam 784028, India

2Department of Molecular Biology and Biotechnology, Tezpur University, Napaam, Tezpur, Assam 784028, India

3Department of Physics, Tezpur University, Napaam, Tezpur, Assam 784028, India

Adv. Mater. Lett., 2015, 6 (3), pp 235-241

DOI: 10.5185/amlett.2015.5629

Publication Date (Web): Feb 22, 2015

E-mail: swapandolui@gmail.com

Abstract

In the current scenario, metal nanoparticles acquire much attention in terms of their diverse applications because of their extremely small size and large surface to volume ratio. Hence, our present study deals with the investigation of antioxidant and antibacterial activity of gold (Au) nanoparticles. First, anisotropic Au nanorods with various aspect ratios have been synthesized by a standard seeded growth method using CTAB-coated Au seed nanoparticles with size less than 10 nm as nucleation centre. Characterization of synthesized nanorods is made using UV-visible and TEM analysis. The antioxidant and antibacterial activities of Au nanorods have been investigated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) as free radical source and Agar-well diffusion assay. The radical scavenging reaction of nanorods was monitored by a UV-visible spectrophotometer and found that Au nanorods show better antioxidant activity than spherical seeds due to the presence of more number of atoms as well as active sites for interaction with the free radical of DPPH. For a set of nanorods DPPH scavenging percentage is 80-90, while for seeds it is only 30. Again, very less amount (volume) of high aspect ratio nanorods is required for efficient scavenging. A linear relationship is observed between DPPH scavenging percentage and volume of Au nano-dispersions. The synthesized Au nanoparticles also have potent antibacterial activity, the maximum zone of inhibition (20 mm) is observed for longer nanorods, against indicator strains due to the interaction of more number of Au+ cations to the negatively charged bacterial cell wall that causes rupturing of the cell wall and finally death. The minimum inhibitory concentration (MIC) for nanorods is lower when tested against gram negative bacteria viz. Y. enterocolitica (12.5μg/ml), S. enterica typhimurium (15 μg/ml), and K. pneumoniae (10 μg/ml) as compared to gram positive bacteria viz. S. aureus (20 μg/ml), L. monocytogenes AMDK2 (20 μg/ml) and B. cereus AMDK1 (25 μg/ml). From this study, it is concluded that high aspect ratio Au nanorods can act as an effective antioxidant and antibacterial agent and it makes the nanoparticles as an alternative for the development of new biomedical drugs in near future.

Keywords

Antibacterial, antioxidant, nanocrystal, DPPH.

Current Issue

Cloud Medicine set to Revolutionize Doorstep Personalized Healthcare


Various surfactants for 0 – 3 dimensional nanocarbons: Separation, exfoliation and solubilization


Polypyrrole based biofunctional composite layer for bioelectrocatalytic device system


Innovative Graphene-PDMS sensors for aerospace applications 


Effect of hot drawing process and carbonization temperature in electrochemical behavior of electrospun carbon nanofibers


Chemical Reactivity and Electronical Properties of Graphene and Reduced Graphene Oxide on Different Substrates


Laser Raman micro-spectroscopy as an effective non-destructive method of detection and identification of various sp2 carbon modifications in industry and in nature


Electrochemical promotion of ammonia synthesis with proton-conducting solid oxide fuel cells


Biomimetic surfaces with hierarchical structure using microsized texture and nanosized Cu particles for superhydrophobicity


Enhancement the properties of high and low-density polyethylene membranes by radiation grafting process


Synthesis of 9-Aminoacridine and its Application as an Anode Material for Aqueous Rechargeable Lithium–ion Batteries


Facile synthesis of novel tough and highly flexible biodegradable membranes for water microfiltration


Investigating the possibility of using acetic acid in place of HF in chromium-benzenedicarboxylates (MIL-53 and MIL-101) synthesis applicable for CO2 adsorption


Previous issues

Smart Healthcare pulls up Clouds for Virtual Medicine

Selecting the correct electromagnetic inspection technology 

Influence of railway-track grinding on the track material condition and tribological behaviour

Micromechanical Fatigue Modelling of the Size Effect in Micro-Scale 316L Stainless Steel Specimens

Functionalization of Graphene and Reduced Graphene Oxide in Different Matrices

Effect of parasitic polytypes on ballistic electron transport in chemical vapor deposition grown 6H-SiC epitaxial layers

Photomemristive heterostructures based on two-dimensional crystals

Architecture - behaviour - properties relationship in Star-shaped MPA-PMMA and MPA-PS hyper-branched copolymers

Graphene and doped graphene: A comparative DFT study

Ag2CO3 / Magnetic reduced graphene oxide nanocomposite as advanced visible light photocatalytic hybrid materials for efficient degradation of azo dye

Optimization of acid hydrolysis process for the preparation cellulose nanofibrils

Alginate/k-carrageenan and alginate/gelatin composite hydrogel beads for controlled drug release of curcumin

Study of microstructure and mechanical properties of friction stir welded ferrite-martensite DP700 steel

Upcoming Congress

Knowledge Experience at Sea TM