Ring opening polymerization of lactide by using zinc prolinate catalyst
Polymer Science and Engineering Division, National Chemical Laboratory, Pune 411088, India
Adv. Mater. Lett., 2014, 5 (1), pp 44-51
Publication Date (Web): Dec 28, 2013
Copyright © IAAM-VBRI Press
Zinc salts of L-proline, D-proline were used in homopolymerization of L, L-lactide and D, L-lactide. Linear PLA oligomer with Mn 2900-3400 Da, can be prepared with zinc (L-prolinate)2 catalyst. Less racemization were occurred in presence of Zn (L-prolinate)2 than Zn (D-prolinate)2. The catalyst structure of Zn (L-prolinate)2 and Zn (D-prolinate)2 remains intact after polymerization. The zinc is bioactive molecule so these polymers prepared by using this catalyst are bioabsorbable. The resulting polymers were characterized by infrared spectroscopy (IR), size exclusion chromatography (SEC), differential scanning calorimetry (DSC), thermo gravimetric analysis (TGA), 13C NMR, 13C Cross Polarization /Magic Angle Spinning (13C CP/MAS) and MALDI ToF-MS.
Zinc prolinate, lactides, ROP, MALDI-ToF-MS, linear polymer