Antifungal Activity of Iron-gold and Cobalt-gold co-doped ZnO Nanoparticles

Antifungal Activity of Iron-gold and Cobalt-gold co-doped ZnO Nanoparticles

A. Ferin Fathima1,2, R. Jothi Mani1,3, K. Sakthipandi4,*

1Department of Physics, Sadakathullah Appa College, Tirunelveli 627 011, Tamil Nadu, India

2Manonmanium Sundaranar University, Tirunelveli 627 012, Tamil Nadu, India

3Department of Physics, Fatima College, Madurai 625 018, Tamil Nadu, India

4Department of Physics, Gandhigram Rural Institute (Deemed to be University), Gandhigram 624 302, Tamil Nadu, India

Adv. Mater. Lett., 2021, 12 (6), 21061636

DOI: 10.5185/amlett.2021.061636

Publication Date (Web): Mar 24, 2021

E-mail: sakthipandi@gmail.com

Abstract


Zn0.98Fe0.01Au0.01O and Zn0.98Co0.01Au0.01O nanoparticles (NPs) have been synthesized via poly ethylene glycol assisted route. The average crystallite size of Zn0.98Fe0.01Au0.01O and Zn0.98Co0.01Au0.01O NPs were estimated from X-ray diffraction results and the values are 31.38 nm and 36.14 nm respectively. The UV absorption spectra confirmed the formation of the NPs with the characteristic peaks at 374 and 366 nm respectively. This spectral observation indicates that the band gap of ZnO nanoparticles decreases by doping iron/gold and cobalt/gold nanoparticles. The morphology and elemental composition of Zn0.98Fe0.01Au0.01O and Zn0.98Co0.01Au0.01O NPs were investigated. The antifungal activity of synthesized Zn0.98Fe0.01Au0.01O and Zn0.98Co0.01Au0.01O NPs were found against four postharvest pathogenic fungi like Aspergillus niger, Aspergillus flavus, Rhizopus microsporus and Pencillium sp. The doping of iron and gold in ZnO nanoparticles enhances the zone of inhibition for the fungal pathogens compared to pure ZnO nanoparticles. Antifungal activity of Zn0.98Fe0.01Au0.01O and Zn0.98Co0.01Au0.01O nanoparticles were higher when compared with standard antibiotic mycostatin whose zone of inhibition is 18 mm against Aspergillus niger, Aspergillus flavus, Rhizopus microsporus and Pencillium sp.

Keywords

Gold nanoparticles, Structural properties, Optical properties, Antifungal activity, Aspergillus niger, Aspergillus flavus, Rhizopus, Pencillium sp.

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