Inhibitive Effect on the Rate of Hydrolysis of Tetracaine by the Surfactant-Coated Magnetic Nanoparticles (Fe3O4)

Inhibitive Effect on the Rate of Hydrolysis of Tetracaine by the Surfactant-Coated Magnetic Nanoparticles (Fe3O4)

Mohd Shaban Ansari, Kashif Raees, M. Z. A. Rafiquee*

Department of Applied Chemistry, Z.H. College of Engineering and Technology, Aligarh Muslim University, Aligarh 202002, Uttar Pradesh, India 

E-mail: drrafiquee@gmail.com

Adv. Mater. Lett., 2021, 12 (4), 21041619

DOI: 10.5185/amlett.2021.041619

Publication Date (Web): Feb 01, 2021

Abstract


The influence of the magnetic nanoparticles Fe3O4 and surfactant coated nanoparticles on the rate of alkaline hydrolysis of tetracaine were investigated spectrophotometrically. The Fe3O4 nanoparticles were synthesized by co-precipitation method. These synthesized nanoparticles were characterized by physical techniques. The XRD patterns showed the crystalline nature and the presence of two bands at 635 cm-1 and 585 cm-1 were assigned to the Fe-O bond vibrations in Fe3O4. The SEM and TEM studies confirmed the spherical structure of nanoparticles. The VSM studies show the magnetic nature. The reaction rate increased linearly with increase in [NaOH]. The rate constant values decreased with the increase in the SDS coated Fe3O4 nanoparticles from 4.0 × 10-4 s-1 to 1.1 × 10-4 s-1 in the presence of PEG 1500. Similarly, the increase in the amount of CTABr coated Fe3O4 nanoparticles decreased the rate constant values from 4.0 × 10-4 s-1 to 1.02 × 10-4 s-1 in the presence of PEG 1500. The binding constant and rate constant were found to be lower in SDS coated nanoparticles than the CTABr coated particles. The observed results for - [surfactant] in the presence of magnetic nanoparticles and surfactant coated nanoparticles were treated using the pseudophase kinetic model.

Keywords

Base catalysed hydrolysis of tetracaine, Fe3O4 magnetic nanoparticles, SDS@Fe3O4, CTABr@Fe3O4

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