COVID-19: A Significant Revival Approach - Concurrent Case Study in India

COVID-19: A Significant Revival Approach - Concurrent Case Study in India

Bindu Mangla1,*,#, Sudheesh K. Shukla2,3,*,#, Jagriti Narang4, Nitika Thakur5, Meenakshi6, Chaudhery Mustansar Hussain7,*

1Department of Chemsitry, J.C. Bose University of Science and Technology YMCA, Faridabad, India

2School of Environmental Science and Engineering, Shandong University, Jimo, Qingdao 266237, P.R. China

3VBRI, 7/16 Kalkaji Extn., New Delhi 110 019, India

4Department of Biotechnology, Jamia Hamdard University, New Delhi 110062, India

5Department of Biotechnology, Shoolini University of Biotechnology and Management Sciences, Bajhol, Solan,
Himachal Pradesh, India

6The Swiss Institute for Dryland Environmental and Energy Research, The Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev, Midreshet Ben-Gurion 8499000, Israel

7Department of Chemistry and Environmental Science, New Jersey Institute of Technology, Newark, New Jersey 07102, USA

#Contributed equally

Adv. Mater. Lett., 2021, 12 (2), 21021598

DOI: 10.5185/amlett.2021.021598

Publication Date (Web): Dec 14, 2020

E-mail: bindumangla@gmail.com (B.M.); sudheeshkshukla@gmail.com (S.K.S.); chaudhery.m.hussain@njit.edu (C.M.H.)

Abstract


In current pandemic, as there is no approved specific antiviral agent for coronavirus disease (COVID-19) available till to date; Indian Ayurveda has emerged out as effective tool to control the prevailing pandemic at initial stage mainly by gearing up the immune system. Convalescent plasma therapy (CPT) has shown a glimpse of hope and some case study supported the hypothesis that CPT could be a prospective treatment option. The current study reported first time on a real time case study in India along with the outcome that CPT could be potentially improved the treatment of severe COVID-19. The CPT results presented here have shown that clinical symptoms were significantly improved along with increase of oxyhemoglobin saturation, also increased lymphocytes count whereas decreased C-reactive proteins within 3 days without any severe adverse side effect.

Keywords

COVID-19 management, Convalescent plasma therapy, clinical symptoms, severe disease, treatment, clinical symptoms, pandemic health combat.

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