Microwave-assisted synthesis and mechanistic study of multicolor emissive Au nanoclusters using thiol-containing biomolecules  

Yong Yu1, Preston Yi Jie Ching1, 2, Yen Nee Tan1, 3*

1Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), Fusion polis Way, 138634 Singapore

2National Junior College, 37 Hillcrest Road, 288913 Singapore

3Department of Chemistry, Faculty of Science, National University of Singapore, 3 Science Drive 3, 117543 Singapore

Adv. Mater. Lett., 2018, 9 (9), pp 647-651

DOI: 10.5185/amlett.2018.2081

Publication Date (Web): Jun 14, 2018

E-mail: tanyn@imre.a-star.edu.sg

Abstract


Developing effective synthesis method for few-atom gold nanoclusters (AuNCs) with tunable emissions is vitally important to gain better understanding of their formation mechanism and provide more design flexibilities to suite for various applications such as multiplex cellular imaging and/or light-emitting diodes. This paper reports a fast method (<30 minutes) of preparing multicolour (red, orange, near infrared) emissive AuNCs via a microwave-assisted biotemplating synthesis approach. A series of analytical tools such as UV-vis and photoluminescence spectroscopies, transmission electron microscopy (TEM) and polyacrylamide gel electrophoresis (PAGE) have been utilized to characterize the resultant AuNCs and unravel the formation mechanism that lead to their multicolour emissive properties. It was found that the surface charge of the thiol-containing peptide reagent and the peptide-to-Au ratio are crucial factors to control the size and emission colour of the resultant AuNCs. By bringing the solution pH to near the isoelectric point of peptide ligand (~3), the red (lem = 725 nm) emissive AuNC which is initially stable at alkaline conditions (pH-12) tends to aggregate due to deficiency of surface charge, thus forming a larger and orange (lem = 640 nm) emissive AuNC. By further applying an even lower peptide-to-Au ratio to fine-tune the protection power of thiolate ligands, a near-infrared (lem = 846 nm) emissive AuNC has been synthesized. Compared to other microwave-assisted synthesis of AuNCs, current study is featured by its simplicity, rapidity, and versatility to tune the emission wavelength of resultant AuNCs in a much broader range (up to 206 nm).

Keywords

Gold nanoclusters, tunable emission, microwave-assisted synthesis, biotemplating.

Current Issue
The Journey of a Decade to Advancing Materials
Are the Electrospun Polymers Polymeric Fibers?
Mechanical and Thermal Properties of Composite Material and Insulation for a Single Walled Tank for Cryogenic Liquids
Prediction of Long-Term Behavior for Dynamically Loaded TPU
Investigation of Doped Titanium Dioxide in Anatase Phase. Study ab initio using Density Functional Theory
Comparison between Single Al2O3 or HfO2 Single Dielectric Layers and their Nanolaminated Systems
Preparation of Stable and Optimized Antibody-gold Nanoparticle Conjugates for Point of Care Test Immunoassays
Resonance-Based Temperature Sensors using a Wafer Level Vacuum Packaged SOI MEMS Process
Integrated System Based on the Hall Sensors Incorporating Compensation of the Distortions
The Efficacy of Cinnamomum Tamala as a Potential Antimicrobial Substance against the Multi-Drug Resistant Enterococcus Faecalis from Clinical Isolates
The Effect of Complexing Reagent on Structural, Electrical and Optical Properties of CuS Thin Film
Laser Cladding of Fluorapatite Nanopowders on Ti6Al4V
Preparation and Evaluation of Sulfonate Polyethylene Glycol Borate Ester as a Modifier of Functional Properties of Complex Petroleum Lithium Grease

Upcoming Congress

Knowledge Experience at Sea TM