Advancement in the sulfone-based dendrimers: From synthesis to application

Shaziya Khanam, Sunil K. Rai,  Ashish K. Tewari*

Department of Chemistry (Center of Advanced Study), Institute of Science, Banaras Hindu University, Varanasi-221005, Uttar Pradesh, India

Adv. Mater. Lett., 2017, 8 (11), pp 1005-1019

DOI: 10.5185/amlett.2017.1609

Publication Date (Web): Aug 05, 2017



The development of sulfone-based macromolecules (polymer to dendrimers) has been inspired and prompted by much interesting importance of sulfone chemistry. Literature reveals that dendrimers are more demanding than the polymer in many aspects, because of its unique structural properties. Inspite of increasing importance and applications of dendrimers, it has a lot of hindrance regarding the tedious way of synthesis, which requires large excess of reagent and several problems in isolation. Therefore, time to time several tactics of synthesis has been developed. It was also well known that sulfonylation reaction is not only fast and easy to handle but also aryl sulfonylchloride derivatives are inexpensively available. Nowadays, sulfone-based dendrimers are exponentially expanding its application in disciplines of science which lie in organic synthesis, material sciences, combinatorial chemistry,  medicinal chemistry and chemical biology. In this review, we have compiled the types of dendrimer and chiefly focused on the synthesis of sulfone-based dendrimers and their applications, in short. Further, future prospect of sulfone-based dendrimers in various branches of science has been outlined.


Dendrimer, generation, sulfone, sulfonimide, sulphonamide, suzuki cross coupling.

Previous issues

Celebrating 10th Years of Diamond Open Access Publishing in Advanced Materials  

Cerebral Oxygenation Studies Through Near Infrared Spectroscopy: A Review

Analysis of Fine Sulfoaluminate Cement by Strength and Thermogravimetric Analysis

Characterization of the Interfacial Surface Energy for Composite Electrical Conduction Measurements using Two Full Range Percolation Threshold Models

Quantitative Detect of Fatigue of Membrane of Erythrocyte in Uniform Shear Field

Ecofriendly-developed Polyacrylic Acid-coated Magnetic Nanoparticles as Catalysts in Photo-fenton Processes

Evaluation of Drug Interactions with Medications Prescribed to Ambulatory Patients with Metabolic Syndrome in Urban Area

Fiber-reinforced Cementitious Composite: Sensitivity Analysis and Parameter Identification 

Evaluation of Drug Utilization Patterns Based on World Health Organization Drug use Indicators at Outpatients Clinics

Are Quantitatively Micro-machined Scaffolds Effective for Cell Technology?

Synthesis and Characterization of Gold Nanoparticles from Lobelia Nicotianifolia Leaf Extract and its Biological Activities

Advanced Oxidations of Tartrazine Azo-dye

Antifungal Activity of Salvia jordanii Against the Oral Thrush Caused by the Cosmopolitan Yeast Candida albicans among Elderly Diabetic Type 2 patients

Upcoming Congress

Knowledge Experience at Sea TM