Electrochemcial sensing of anti-diabetic drug using hierarchically deposited PB nanocubes on carbon
1Amity Institute of Nanotechnology, Amity University, Noida (UP), 201301, India
2Skinic, Agra (UP), 282002, India
3Department of Biochemistry, M. D. University, Rohtak 124 001, Haryana, India
Adv. Mater. Lett., 2017, 8 (4), pp 572-576
Publication Date (Web): Mar 15, 2017
Copyright © IAAM-VBRI Press
Prussian Blue nanocubes / carbon nanospheres (PB-CNS) heterostructure composed of perfectly cube and spherical composite on indium tin oxide (ITO) surface were developed for in vitro sensing of anti-diabetic drug i.e. Sitagliptin (STA). Detailed morphological, electrochemical, structural and optical characterization of PB-CNS/ITO electrode was done using DLS, SEM, EIS, CV. The sensor showed rapid response time (within 5 s) and the linear range from 0.001 to 10 mM with a shelf life of about 10 weeks under refrigerated conditions. We have also attempted to employ this electrode for assessment of STA in urine samples. The developed sensor exhibited high reproducibility and good storage stability.
Sitagliptin, prussian blue nanocubes, carbon nanospheres, sensor, ITO electrode.